At MemeMixr.com, we can't get enough of the "Futurama - Frye Drinks Too Much Coffee" meme. The image of Frye looking jittery and over-caffeinated perfectly captures the feeling of being unable to calm down after drinking too much coffee. This meme is great for reacting to situations where someone is feeling anxious or jittery, or for poking fun at the effects of too much caffeine.